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Among patients with IHC 2+ (borderline HER2 status) tumors, the ORR was 5.6%, median OS was 5.2 months, and median PFS was 1.7 months

In the context of MASLD, glucagon receptor activation may complement GLP-1 RA by promoting hepatic fatty acid oxidation and suppressing lipogenesis, thereby reducing intrahepatic fat accumulation

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Coverage varies across the entire class of GLP-1 receptor agonists, with diabetes indications typically covered but obesity indications excluded in most states